MONITORING OF BUFFY COAT THERAPY IN CHRONIC MYELOGENOUS LEUKEMIA (CML) WITH QUANTITA TIVE POLYMERASE CHAIN REACTION (PCR)

SNM Schmidt, ULDHW Siegert, A Neubauer - karger.com
… and efficiently detected after reverse transcription into cDNA by … Coamplification did not
show any competition between the … Most patients (n=26) were on interferon alpha (a-IFN) or …

[HTML][HTML] Diagnostic performance of the molecular BCR-ABL1 monitoring system may impact on inclusion of CML patients in stopping trials

B Spiess, S Rinaldetti, N Naumann, N Galuschek… - PLoS …, 2019 - journals.plos.org
… Standardization and quality control studies of 'real-time' quantitative reverse transcriptase
polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia

Prognostic markers associated with tyrosine kinase inhibitor treatment response and maintenance of treatment free remission in chronic myeloid leukaemia

DTO Yeung - 2016 - digital.library.adelaide.edu.au
… the performance and interpretation of the multivariate competingmonitoring and longterm
outcomes in chronic myelogenous … using nanofluidic digital polymerase chain reaction assay. …

Standardization of molecular monitoring for chronic myeloid leukemia: 2021 update

M Salmon, HE White, NCP Cross… - … Myeloid Leukemia, 2021 - Springer
… by reverse transcriptase polymerase chain reaction (RT-PCR) were initiated more than 30
… in complete cytogenetic remission (CCyR) on interferon alpha [7,8,9,10,11,12]. Competitive

[HTML][HTML] Chronic myeloid leukemia prognosis and therapy: criticisms and perspectives

D Russo, JV Garcia-Gutierrez, S Soverini… - Journal of Clinical …, 2020 - mdpi.com
… (allo-SCT) and interferon-alpha (IFNα) have been proven to … transcription polymerase chain
reaction (RT-qPCR) [6,7,8]. … Preservation of quiescent chronic myelogenous leukemia stem …

How we monitor the therapy effectiveness in patients with chronic myeloid leukemia-A Single center experience

S Mešanović, A Žugić-Jahić, S Hasić, V Simendić… - Genetics & …, 2023 - genapp.ba
… The quantitative real-time polymerase chain reaction method (… adherence in chronic
myelogenous leukemia in the chronic … after failure of interferon-alpha treatment. Blood 1;111(3):…

Chronic myeloid leukemia: 2020 update on diagnosis, therapy and monitoring

E Jabbour, H Kantarjian - American journal of hematology, 2020 - Wiley Online Library
… Baseline reverse transcriptase-polymerase chain reaction is … It acts via competitive inhibition
at the ATP-binding site of the … Given the equivalent efficacy and lower toxicity of lower dose …

[HTML][HTML] Treatment-Free Remission—A New Aim in the Treatment of Chronic Myeloid Leukemia

P Kwaśnik, K Giannopoulos - Journal of Personalized Medicine, 2021 - mdpi.com
… The role of modern droplet digital polymerase chain reaction (… to the treatment of TKI, then
interferon alpha (IFN-α) therapy is … to the patient allows for careful monitoring of the patient. …

Human leukocyte antigen-B phenotype and minimal residual disease in chronic myeloid leukemia patients treated with imatinib: Is there an association?

E Hadad, A Ehsanpour, T Vosoughi… - Clinical Cancer …, 2020 - search.ebscohost.com
… ) in chronic myelogenous leukemia (CML) patients treated … by real‑time polymerase chain
reaction technique. Results: No … of the drugs used to treat cancer such as interferonalpha (…

[HTML][HTML] The role of cytogenetics and molecular biology in the diagnosis, treatment and monitoring of patients with chronic myeloid leukemia

LE Dorfman, MA Floriani, TMRDR Oliveira… - Jornal Brasileiro de …, 2018 - SciELO Brasil
… techniques such as FISH or polymerase chain reaction (PCR) ( 19 19 … in chronic myelogenous
leukemia cells through nuclear … The use of interferon-alpha resulted in disease regression …